![]() Active control MUS training did, however, lead to a within-subject increase in the DLPFC, while both the VID and MUS training produced growth in the cerebellum. After training, a within-subject increase in grey matter within the hippocampus was significant only in the VID training group, replicating results observed in younger adults. Additionally, an active control group took a series of self-directed, computerized music (piano) lessons (MUS n = 12), while a no-contact control group did not engage in any intervention (CON n = 13). The video game experimental group (VID n = 8) engaged in a 3D-platform video game training over a period of 6 months. Older adults who were 55 to 75 years of age were randomized into three groups. In the current study, we tested the impact of 3D-platform video game training (i.e., Super Mario 64) on grey matter in the hippocampus, cerebellum, and the dorsolateral prefrontal cortex (DLPFC) of older adults. Playing 3D-platform video games has previously been shown to promote grey matter in the hippocampus in younger adults. Maintaining grey matter within the hippocampus is important for healthy cognition. ![]()
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